Glucocorticoids, naturally occurring and synthetic, are adrenocortical steroids that are readily absorbed from the gastrointestinal tract.

When necessary, the pH of each formula was adjusted with sodium hydroxide so that the pH of the reconstituted solution is within the USP specified range of 7 to 8. IMPORTANT - Use only the accompanying diluent or Bacteriostatic Water For Injection with Benzyl Alcohol when reconstituting SOLU-MEDROL. The packaged diluent (Bacteriostatic Water for Injection) contains benzyl alcohol as a preservative. Recommended diluent (Bacteriostatic water) contains benzyl alcohol as a preservative.Ģ gram Vial with Diluent-Each 30.6 mL (when mixed as directed) contains methylprednisolone sodium succinate equivalent to 2 grams methylprednisolone also 25.6 mg monobasic sodium phosphate anhydrous 278 mg dibasic sodium phosphate dried. Recommended diluent (Bacteriostatic water) contains benzyl alcohol as a preservative.Ģ gram Vial-Each 30.6 mL (when mixed as directed) contains methylprednisolone sodium succinate equivalent to 2 grams methylprednisolone also 25.6 mg monobasic sodium phosphate anhydrous 278 mg dibasic sodium phosphate dried.

Recommended diluent (Bacteriostatic water) contains benzyl alcohol as a preservative.ġ gram Vial-Each 16 mL (when mixed as directed) contains methylprednisolone sodium succinate equivalent to 1 gram methylprednisolone also 12.8 mg monobasic sodium phosphate anhydrous 139.2 mg dibasic sodium phosphate dried.

Preservative-free Formulations 40 mg Act-O-Vial System (Single-Dose Vial)-Each mL (when mixed) contains methylprednisolone sodium succinate equivalent to 40 mg methylprednisolone also 1.6 mg monobasic sodium phosphate anhydrous 17.46 mg dibasic sodium phosphate dried and 25 mg lactose hydrous.ġ25 mg Act-O-Vial System (Single-Dose Vial)-Each 2 mL (when mixed) contains methylprednisolone sodium succinate equivalent to 125 mg methylprednisolone also 1.6 mg monobasic sodium phosphate anhydrous and 17.4 mg dibasic sodium phosphate dried.ĥ00 mg Act-O-Vial System (Single-Dose Vial)-Each 4 mL (when mixed) contains methylprednisolone sodium succinate equivalent to 500 mg methylprednisolone also 6.4 mg monobasic sodium phosphate anhydrous and 69.6 mg dibasic sodium phosphate dried.ġ gram Act-O-Vial System (Single-Dose Vial)-Each 8 mL (when mixed) contains methylprednisolone sodium succinate equivalent to 1 gram methylprednisolone also 12.8 mg monobasic sodium phosphate anhydrous and 139.2 mg dibasic sodium phosphate dried.įormulations preserved with Benzyl Alcohol 500 mg Vial-Each 8 mL (when mixed as directed) contains methylprednisolone sodium succinate equivalent to 500 mg methylprednisolone also 6.4 mg monobasic sodium phosphate anhydrous 69.6 mg dibasic sodium phosphate dried.

Adrenocortical insufficiency